Molecular Epidemiology of Human Papillomavirus in Pterygium
Authors
Abstract:
Abstract Background and Objective: Ophthalmic pterygium is a potentially vision-threatening lesion of unknown etiology that often extends on the corneal surface and has a worldwide distribution. Despite various studies, the pathogenesis of pterygium remains unclear and the involvement of human papillomavirus is controversial. We aimed to investigate the involvement of papillomavirus in pterygium formation. Material and Methods: This case-control study was conducted on 50 tissue specimens of pterygium from the patients who had pterygium surgery as the case group and 10 conjunctival biopsy specimens of individuals without pterygium including the patients with cataract surgery, as controls. The evidence of papillomavirus infection was tested by polymerase chain reaction (PCR). Results: All samples, case and control, were not positive for papillomavirus. Both groups were positive for beta-globulin gene used to check the quality of extracted DNA. Conclusion: In this study, due to the absence of papillomavirus in the context of Pterygium it seems that other factors are involved in causing the disease. Keywords: Pterygium; Human Papilloma Virus; PCR.
similar resources
Molecular virology and epidemiology of human papillomavirus and cervical cancer.
Introduction In 1994, an estimated 55,000 women in the United States will be diagnosed with carcinoma in situ of the cervix, with an additional 15,000 invasive cases expected. An estimated 4600 women died from this disease in 1994, despite remarkable progress made in screening (1). Regarding extent of disease among women with invasive cancer in the United States from 1983 to 1987, 48% of tumors...
full textMolecular Virology and Epidemiology of Human Papillomavirus and Cervical Cancer1
Introduction In 1994, an estimated 55,000 women in the United States will be diagnosed with carcinoma in situ of the cervix, with an additional 15,000 invasive cases expected. An estimated 4600 women died from this disease in 1994, despite remarkable progress made in screening (1). Regarding extent of disease among women with invasive cancer in the United States from 1983 to 1987, 48% of tumors...
full textMolecular epidemiology of Human Papillomaviruses in breast cancer, Golestan province of Iran
Abstract Background and objectives: Breast cancer is the most prevalent one in women. Some of the common causative factors are genetic background, nutritional and environmental factors. Viruses are believed as a risk factor in this cancer, too. Recent studies reported that Human Papillomaviruses can be one of the possible risk factors of breast cancer. This study focused on investigation of the...
full textThe epidemiology of human papillomavirus infections.
Infection with oncogenic human papillomavirus (HPV) types is a necessary cause of cervical cancer, the second most frequently occurring cancer in women worldwide. Rates of acquisition of HPV are high, particularly among sexually active young adults. Reported estimates of incident HPV infection among initially negative women have reached as high as 60% over a 5-year follow-up period. In this art...
full textThe epidemiology of genital human papillomavirus infection.
Clinical and subclinical human papillomavirus (HPV) infections are the most common sexually transmitted infections in the world, and most sexually-active individuals are likely to be exposed to HPV infection during their lifetimes. More than 40 genotypes of HPV infect the epithelial lining of the anogenital tract and other mucosal areas of the body; of these, 13-18 types are considered to be hi...
full textMy Resources
Journal title
volume 9 issue 3
pages 135- 140
publication date 2015-09
By following a journal you will be notified via email when a new issue of this journal is published.
No Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023